Nature Communications and Angewandte Chemie Report New Advances by ECUST in Palladium-Catalyzed Asymmetric Alkene Coupling

Recently, the research group led by Professor Yifeng Chen from the Feringa Nobel Prize Scientist Joint Research Center at the School of Chemistry and Molecular Engineering, ECUST, published two research papers online, reporting a series of new advances in palladium-catalyzed asymmetric dicarbofunctionalization of alkenes. One paper, titled “Palladium-Catalyzed Asymmetric Migratory Diarylation of Unactivated Directing-Group-Free Internal Alkenes” was published in Nature Communications. The other, titled “Palladium-Catalyzed Enantioselective Four-Component Carbonylative Dicarbofunctionalization of Internal Alkenes with 1 atm CO” was published in Angewandte Chemie.

The work was primarily completed by doctoral student Linlin Fan and postdoctoral fellow Xi Yang respectively, together with other members of the research team, with Professor Yifeng Chen serving as the corresponding author. The research was guided by Professor Jingping Qu and Academician Weihong Zhu. 

The research was supported from the National Natural Science Foundation of China, the Feringa Nobel Prize Scientist Joint Research Center, and the Frontiers Science Center for Materiobiology and Dynamic Chemistry under the Ministry of Education, among other funding sources.